The MAFEIP tool has been under development, starting from 2015, by the EU Commission’s Joint Research Centre – IPTS, in close cooperation with the Commission's services and the European Innovation Partnership for Active and Healthy Aging (EIP on AHA), with the aim of creating a shared and reliable methodology to monitor impacts across the diverse EIP on AHA domains and interventions. The MAFEIP framework has since then evolved and gradually matured into a flexible tool, that can be applied to assess the impact of innovative interventions in a large number of health and care contexts, including oncology.

The MAFEIP tool comprises a remotely accessible web-based user interface which rests on the principles of Decision Analytic Modelling (DAM), an approach that is commonly used in health economic evaluations. More specifically, the MAFEIP tool is based on a Markov model which provides the flexibility required to be adaptable to a wide number of healthcare applications and interventions scenarios.

In the BD4QoL project, the MAFEIP tool will be applied to assess the cost effectiveness of BD4QoL along four scenarios: decrease the proportion of QoL deterioration, delay QoL deterioration, decrease deterioration of specific QoL items, predict QoL deterioration.